Activities of plasminogen activator, plasmin and kallikrein in synovial fluid from patients with temporomandibular joint disorders

H Sakamaki, N Ogura, H Kujiraoka, M Akiba… - International journal of …, 2001 - Elsevier
To measure the activities of plasminogen activator (PA), plasmin and kallikrein, multiple
synovial fluid samples were taken from 32 patients with internal derangement (ID) and
osteoarthrosis (OA), and nine asymptomatic volunteers. The enzyme activity in synovial fluid
from the temporomandibular joint (TMJ) was quantitated by a fluorogenic substrate assay
using an enzyme substrate. In fluid samples from the patient group, PA was detected in 24
(31.5%), plasmin in 20 (26.3%) and kallikrein in 53 (96.4%), while none of these enzymes …